Sugar could be sweet solution to respiratory disease
Restriction or inhalation of common sugar could one day treat a range of respiratory diseases, according to new research led by University of Manchester biologists. The study in mice reveals how the ability of cells to use glucose helps to regulate the immune system during lung inflammation. Their research suggests that blocking sugar receptors in the lung could reduce inflammation in chronic conditions such as asthma, allergies and parasitic worm infections. On the other hand, the immune response against some infections could be enhanced by inhalation of sugar solutions. The international study by scientists from The University of Manchester, AstraZeneca, The University of Southampton and the National Institute of Health in the United States is published in Nature Immunology today. The study was funded by a range of bodies including the Wellcome Trust, Medical Research Council, BBSRC, AstraZeneca, Asthma UK and National Institute of Health. Lead researcher Profess...