Can Glenmark Pharma Taste Success Where Its Peers Have Not?


One of the earliest Indian drugmakers to have focused on innovative R&D, Glenmark Pharma is now spinning off its R&D business into a separate company that would be based in the US.

Glenmark Pharma has hired a former executive from Gilead & Novartis to head the new company. All innovative molecules in the pipeline, including preclinical assets and technology, the R&D centres in Switzerland, Paramus, and Navi Mumbai, and the biologics manufacturing facility in Switzerland, along with 400 employees associated with innovative drug discovery will be part of the new company in the next six to nine months.

Glenmark's current innovation pipeline consists of eight assets, including new chemical entities and new biologic entities in various stages of development. These are in the areas of immunology, oncology and pain management.

But will the latest move enable Glenmark to succeed in its quest for discovering an innovative drug? Several of its peers, including Sun Pharma, Piramal Healthcare, DRL, Strides Arcolab and Wockhardt, have in the past adopted this strategy of de-merging their R&D arms – roping in Indian expats to head the units. However, none has been successful in a big way.

Still, for Glenmark, the move holds some clear advantages. The spinning-off will separate the riskier R&D business from the less risky ones. With some of its molecules in phase II stage of development, the R&D company can leverage its extensive patient data to help command better valuations.

The spin-off will also lead to complete transparency on what the company is spending toward innovative R&D. It will also reduce the intensity of investments the parent company has to make toward innovative R&D – leading to improvement in the margin profile of the parent company. Glenmark Phama annually spends $100-120 million on innovative R&D.

Glenmark has also attempted to be different from its peers by basing the new company in the US and hiring a veteran from the Big Pharma to head it. The idea is to harness global talent and gain from the pharma and biotech ecosystem in the US.

Glenmark has been among the few players to be consistent with its strategy of investing in innovation. Over the years, there has been a churn in its research portfolio. But the latest move may be a decisive step toward commercially launching an innovative drug.

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