Future of drugs-Heart Disease & Stroke_Vernakalant
Drug
Name
|
Vernakalant
|
Structure
|
|
Drug Code
|
RSD1235
|
Synonym
|
Kynapid, Brinavess
(3R)-1-{(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]
cyclohexyl}pyrrolidin-3-ol
|
Molecular Formula
|
C20H31NO4
|
Innovator
|
Cardiome Pharma Corp
Merck
|
Condition
|
Prevention of
post-operative atrial fibrillation in patients undergoing coronary artery
bypass graft surgery.
|
Mechanism of Action
|
Blocks atrial potassium
and sodium channels
|
Clinical Phase
|
Not yet approved. (Filed
for Orphan Drug Designation)
Approved in Europe.
|
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