AI and advanced analytics transforming pharma industry: FICCI-KPMG report
Pharmaceutical companies need to adopt technologies such as AI
and advanced analytics, to not only improve efficiencies and reduce costs, but
also to adapt a more patient centric business models, says a new FICCI-KPMG
paper on artificial Intelligence and advanced analytics in pharmaceuticals.
Globally, there is pressure to reduce costs and demonstrate
greater value, swinging from treatment to prevention and personalised
treatments, which is posing a challenge to the overall business model of the
pharmaceutical companies. AI and advanced analytics can process large amount of
complex, both structured and unstructured data at a rapid pace to generate
actionable insights and thereby reduce costs, to improve time to market and
gain competitive strength in the market place. While major global companies are
investing heavily in this sector, it is only recently that pharmaceutical
companies have started to demonstrate significant interest in AI application for
various R&D (research and development) and supply chain needs, observed the
report.
AI in pharmaceutical industry can transform processes from the
initial R&D level to the after-consumption stage from R&D, drug dosage
and safety, manufacturing, supply chain and commercialisation and for
regulatory approvals, said the knowledge paper, which estimates AI in drug
dosage error reduction alone can save $16 billion by 2026.
It said pharma companies are increasingly collaborating with
technology companies, especially start-ups in this area. Atomwise, a start-up
which established the use of deep neural networks for drug design, raised $45
million investment to develop its AI-driven drug discovery technology.
GlaxoSmithKline signed a $43 million drug discovery collaboration with
Exscientia, a UK based AI-based start-up, to identify small molecules for ten
selected targets across undisclosed therapeutic areas. Pharma companies such as
GSK, Sanofi, Takeda Pharma and Merck have entered into various partnerships
with AI start-ups.
Sanofi and Exscientia entered into $283 million
strategic research collaboration agreement aimed at developing new therapies
for diabetes and other metabolic diseases. Drug developers are relying on AI
for multiple uses: to develop better biomarkers; to identify drug targets; to
design new drugs as well as for re-purposing drugs i.e. finding new uses for
existing drugs or late-stage drug candidates. An increasing need is also being
felt for pharmaceutical companies to explore coming together to share data and
look for patterns for precision medicines. Applications in pharmaceutical
R&D will include identification of new target molecules from a repository,
experimenting with the drug or device using technologies such as 3D printed
molecules and lab-on-chips and pre and post approval monitoring.
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